Adenosine disodium triphosphate

Research use only, not for human use.

Adenosine triphosphate (ATP) is a nucleoside triphosphate used in cells as a coenzyme often called the "molecular unit of currency" of intracellular energy transfer.

Adenosine triphosphate (ATP) is a nucleoside triphosphate used in cells as a coenzyme often called the "molecular unit of currency" of intracellular energy transfer.

ATP disodium salt hydrate (5mM; 1 hour) co-treatment with LPS (1 μg/ml) has a synergistic effect on the activation of the NLRP3 inflammasome in HGFs.ATP disodium salt hydrate (2 mM; 0.5-24 hours) induces secretion of interleukin 1β, KC and MIP-2 from bone marrow derived macrophages (BMDMs) in vitro in a caspase-1 activation-dependent manner.?ATP disodium salt hydrate stimulats cytokine and chemokine secretion and inflammasome activation directly and indirectly induces in vitro neutrophil chemotaxis.

ATP disodium salt hydrate (50 mg/kg; i.p.) protects mice against bacterial infection in vivo.ATP disodium salt hydrate induces the secretion of IL1β, KC and MIP-2 and neutrophils recruitment in vivo. Animal Model:Four-week-old Kunming mice (18-22 g)Dosage:50 mg/kg Administration:Intraperitoneal injection, before bacterial (E. coli) challengeResult:Protected mice from bacterial infection.

——

Others

Other Targets

Others

——

——

34369-07-8

551.15

C10H14N5Na2O13P3

>98% (HPLC)

In Vitro:?H2O : 100 mg/mL

c1nc2c(c(n1)N)ncn2C1[C@@H]([C@@H]([C@H](O1)COP(=O)(O)OP(=O)([O-])OP(=O)(O)[O-])O)O.O.[Na+].[Na+]

——

(-20℃)

With Ice Pack

≥ 2 years